An Exploration of Social Cognition in Children with Different Degrees of Genetic Deletion in Williams Syndrome

Autor/inn/en	Serrano-Juárez, Carlos Alberto; Prieto-Corona, Belén; Rodríguez-Camacho, Mario; Venegas-Vega, Carlos Alberto; Yáñez-Téllez, Ma. Guillermina; Silva-Pereyra, Juan; Salgado-Ceballos, Hermelinda; Arias-Trejo, Natalia; De León Miranda, Miguel Angel
Titel	An Exploration of Social Cognition in Children with Different Degrees of Genetic Deletion in Williams Syndrome
Quelle	In: Journal of Autism and Developmental Disorders, 51 (2021) 5, S.1695-1704 (10 Seiten) PDF als Volltext Verfügbarkeit
Zusatzinformation	ORCID (Prieto-Corona, Belén)
Sprache	englisch
Dokumenttyp	gedruckt; online; Zeitschriftenaufsatz
ISSN	0162-3257
DOI	10.1007/s10803-020-04656-4
Schlagwörter	Social Cognition; Children; Genetic Disorders; Pervasive Developmental Disorders; Theory of Mind + Suchen Sie Ihr Suchwort? Soziale Kognition; Child; Kind; Kinder
Abstract	An explanation for the social dysfunction observed in Williams syndrome may be deficits in social cognition. This study explored aspects of social cognition in children with Williams syndrome with different genotypes. The 12 participants included one with a 1.1 Mb deletion that retained the GTF2IRD1, GTF2I, and GTF2IRD2 genes, seven with a 1.5 Mb deletion that preserved the GTF2IRD2 gene, and four with a 1.8 Mb deletion with loss of all three genes. The participant retaining all three genes was found to have better performance on social judgment and first-order theory of mind tasks than the group with loss of all three genes. These results may reflect the influence of the GTF2I gene family on social cognition in Williams syndrome. (As Provided).
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Erfasst von	ERIC (Education Resources Information Center), Washington, DC
Update	2024/1/01